Unmasking the Rare: Leveraging scRNA-seq to Identify Elusive Immune Subpopulations
The landscape of modern immunology has been radically transformed by the advent of high-resolution genomic tools. For decades, researchers relied on bulk RNA sequencing, which provides an average "signature" of gene expression across millions of cells. While useful, bulk sequencing acts like a blender, masking the unique characteristics of individual cells and making it nearly impossible to...
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