Targeting Gamma-Secretase Novel Inhibitor Use by 2026
The Role of Notch Signaling in Tumor Growth A key focus in contemporary desmoid tumor drug development is Targeting Gamma-Secretase, a complex enzyme that plays a critical role in cellular communication. This enzyme is responsible for cleaving several membrane proteins, most notably components of the Notch signaling pathway. In desmoid tumors, aberrant or excessive Notch signaling is implicated...
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